Selective, energy-dependent proteolysis in Escherichia coli

S. Gottesman*, S. Wickner, Y. Jubete, S. K. Singh, M. Kessel, M. Maurizi

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

33 Scopus citations

Abstract

Degradation of proteins in the cytoplasm is carried out by complex, energy-dependent proteases. ATPase activity is involved in the inspection and unfolding of potential targets for proteolysis, which prepares them for a second ATP-consuming process necessary for translocation of the protein substrate into the proteolytic core of the enzyme.

Original languageEnglish
Pages (from-to)533-548
Number of pages16
JournalCold Spring Harbor Symposia on Quantitative Biology
Volume60
DOIs
StatePublished - 1995
Externally publishedYes

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