Self-Assembled Monolayers in Electroanalytical Chemistry: Application of ω-Mercapto Carboxylic Acid Monolayers for the Electrochemical Detection of Dopamine in the Presence of a High Concentration of Ascorbic Acid

Franck Malem, Daniel Mandler*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

393 Scopus citations

Abstract

Self-assembled monolayers of ω-mercapto carboxylic acids, HS(CH2)nCO2H (n = 2, 5, 10), Cn, on gold electrodes were used as a means to Induce electrochemical differentiation between a neurotransmitter, dopamine (DO), and ascorbic add (AA). Optimum differentiation is found for n = 5, and it is attributed to a compromise between a well-organized system that requires long ω-mercapto carboxylic adds and a reasonable rate of electron transfer which is observed with short ω-mercapto carboxylic acids.

Original languageEnglish
Pages (from-to)37-41
Number of pages5
JournalAnalytical Chemistry
Volume65
Issue number1
DOIs
StatePublished - 1 Jan 1993

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