Sensitivity of Burkitt lymphoma Daudi cells to inactive influenza virus

Ynon Shlomi; Zichria Zakay-Rones

doi:10.1007/BF00391601

Sensitivity of Burkitt lymphoma Daudi cells to inactive influenza virus

Ynon Shlomi, Zichria Zakay-Rones^*

^*Corresponding author for this work

Institute for Medical Research Israel-Canada (IMRIC)

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

Interaction of UV-inactivated influenza A/X47 virus at high multiplicity caused a rapid inhibition in cellular protein and DNA synthesis, thus arresting Burkitt-lymphoma-derived Daudi cell multiplication, and eventually killing the cells. The mechanism of the cytolytic effect is presumably, linked to the increase in cell membrane permeability indicated by elevation in ⁵¹Cr release. This might be the consequence of the mass adsorption and/or penetration of viral particles.

Original language	English
Pages (from-to)	61-66
Number of pages	6
Journal	Journal of Cancer Research and Clinical Oncology
Volume	115
Issue number	1
DOIs	https://doi.org/10.1007/BF00391601
State	Published - Feb 1989

Keywords

Cytotoxicity
Daudi-Burkitt lymphoma cells
Influenza virus
UV-inactivated virus

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1007/BF00391601

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abstract = "Interaction of UV-inactivated influenza A/X47 virus at high multiplicity caused a rapid inhibition in cellular protein and DNA synthesis, thus arresting Burkitt-lymphoma-derived Daudi cell multiplication, and eventually killing the cells. The mechanism of the cytolytic effect is presumably, linked to the increase in cell membrane permeability indicated by elevation in 51Cr release. This might be the consequence of the mass adsorption and/or penetration of viral particles.",

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KW - Cytotoxicity

KW - Daudi-Burkitt lymphoma cells

KW - Influenza virus

KW - UV-inactivated virus

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Sensitivity of Burkitt lymphoma Daudi cells to inactive influenza virus

Abstract

Keywords

UN SDGs

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