Sensitivity of Burkitt lymphoma Daudi cells to inactive influenza virus

Ynon Shlomi; Zichria Zakay-Rones

doi:10.1007/BF00391601

Sensitivity of Burkitt lymphoma Daudi cells to inactive influenza virus

Ynon Shlomi
, Zichria Zakay-Rones^*

^*Corresponding author for this work

Institute for Medical Research Israel-Canada (IMRIC)

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

Interaction of UV-inactivated influenza A/X47 virus at high multiplicity caused a rapid inhibition in cellular protein and DNA synthesis, thus arresting Burkitt-lymphoma-derived Daudi cell multiplication, and eventually killing the cells. The mechanism of the cytolytic effect is presumably, linked to the increase in cell membrane permeability indicated by elevation in ⁵¹Cr release. This might be the consequence of the mass adsorption and/or penetration of viral particles.

Original language	English
Pages (from-to)	61-66
Number of pages	6
Journal	Journal of Cancer Research and Clinical Oncology
Volume	115
Issue number	1
DOIs	https://doi.org/10.1007/BF00391601
State	Published - Feb 1989

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Cytotoxicity
Daudi-Burkitt lymphoma cells
Influenza virus
UV-inactivated virus

Access to Document

10.1007/BF00391601

Cite this

@article{a09f2702d7044431894e0226d97b5c8f,

title = "Sensitivity of Burkitt lymphoma Daudi cells to inactive influenza virus",

abstract = "Interaction of UV-inactivated influenza A/X47 virus at high multiplicity caused a rapid inhibition in cellular protein and DNA synthesis, thus arresting Burkitt-lymphoma-derived Daudi cell multiplication, and eventually killing the cells. The mechanism of the cytolytic effect is presumably, linked to the increase in cell membrane permeability indicated by elevation in 51Cr release. This might be the consequence of the mass adsorption and/or penetration of viral particles.",

keywords = "Cytotoxicity, Daudi-Burkitt lymphoma cells, Influenza virus, UV-inactivated virus",

author = "Ynon Shlomi and Zichria Zakay-Rones",

year = "1989",

month = feb,

doi = "10.1007/BF00391601",

language = "אנגלית",

volume = "115",

pages = "61--66",

journal = "Journal of Cancer Research and Clinical Oncology",

issn = "0171-5216",

publisher = "Springer Science and Business Media Deutschland GmbH",

number = "1",

}

TY - JOUR

T1 - Sensitivity of Burkitt lymphoma Daudi cells to inactive influenza virus

AU - Shlomi, Ynon

AU - Zakay-Rones, Zichria

PY - 1989/2

Y1 - 1989/2

N2 - Interaction of UV-inactivated influenza A/X47 virus at high multiplicity caused a rapid inhibition in cellular protein and DNA synthesis, thus arresting Burkitt-lymphoma-derived Daudi cell multiplication, and eventually killing the cells. The mechanism of the cytolytic effect is presumably, linked to the increase in cell membrane permeability indicated by elevation in 51Cr release. This might be the consequence of the mass adsorption and/or penetration of viral particles.

AB - Interaction of UV-inactivated influenza A/X47 virus at high multiplicity caused a rapid inhibition in cellular protein and DNA synthesis, thus arresting Burkitt-lymphoma-derived Daudi cell multiplication, and eventually killing the cells. The mechanism of the cytolytic effect is presumably, linked to the increase in cell membrane permeability indicated by elevation in 51Cr release. This might be the consequence of the mass adsorption and/or penetration of viral particles.

KW - Cytotoxicity

KW - Daudi-Burkitt lymphoma cells

KW - Influenza virus

KW - UV-inactivated virus

UR - https://www.scopus.com/pages/publications/0024602731

U2 - 10.1007/BF00391601

DO - 10.1007/BF00391601

M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???

C2 - 2921273

AN - SCOPUS:0024602731

SN - 0171-5216

VL - 115

SP - 61

EP - 66

JO - Journal of Cancer Research and Clinical Oncology

JF - Journal of Cancer Research and Clinical Oncology

IS - 1

ER -

Sensitivity of Burkitt lymphoma Daudi cells to inactive influenza virus

Abstract

UN SDGs

Keywords

Access to Document

Other files and links

Fingerprint

Cite this