Abstract
The development of an analytical formula to describe the time course of post-synaptic channel opening under constant low concentrations of neurotransmitter is discussed. Based upon this formula, simplified analytical expressions for the dependence of the rising phase and the steady-state level of open channels on transmitter concentration were produced. These expressions provide the means to evaluate the rate constants which govern the rise time of the synaptic current.
Original language | English |
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Pages (from-to) | 517-534 |
Number of pages | 18 |
Journal | Journal of Theoretical Biology |
Volume | 158 |
Issue number | 4 |
DOIs | |
State | Published - 21 Oct 1992 |