Simplified synthesis of oligoethylene glycols

A. Zada, Y. Avny, A. Zilkha*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

Simple economical syntheses in good yield of octa-, nona-, and undecaethylene glycols were developed based on a coupling methodology whereby monobenzyl trior tetraethylene glycols were chain-extended either by coupling them together in the presence of tosyl chloride or through reaction with α,ω-ditosyl triethylene glycol in dioxane in the presence of powdered KOH. The α,ω-O-benzyl-protecting groups were removed by catalytic hydrogenolysis.

Original languageEnglish
Pages (from-to)163-166
Number of pages4
JournalJournal of Surfactants and Detergents
Volume4
Issue number2
DOIs
StatePublished - 2001

Keywords

  • Nonaethylene glycol
  • Octaethylene glycol
  • Oligoethylene glycols
  • Undecaethylene glycol
  • α,ω-Dibenzyl oligoethylene glycols

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