Simplified synthesis of oligoethylene glycols

A. Zada; Y. Avny; A. Zilkha

doi:10.1007/s11743-001-0170-8

Simplified synthesis of oligoethylene glycols

A. Zada
, Y. Avny
, A. Zilkha^*

^*Corresponding author for this work

Institute of Chemistry

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

Simple economical syntheses in good yield of octa-, nona-, and undecaethylene glycols were developed based on a coupling methodology whereby monobenzyl trior tetraethylene glycols were chain-extended either by coupling them together in the presence of tosyl chloride or through reaction with α,ω-ditosyl triethylene glycol in dioxane in the presence of powdered KOH. The α,ω-O-benzyl-protecting groups were removed by catalytic hydrogenolysis.

Original language	English
Pages (from-to)	163-166
Number of pages	4
Journal	Journal of Surfactants and Detergents
Volume	4
Issue number	2
DOIs	https://doi.org/10.1007/s11743-001-0170-8
State	Published - 2001

Keywords

Nonaethylene glycol
Octaethylene glycol
Oligoethylene glycols
Undecaethylene glycol
α,ω-Dibenzyl oligoethylene glycols

Access to Document

10.1007/s11743-001-0170-8

Cite this

@article{4c7fc396e8204cf5ab25db2f32efb2fa,

title = "Simplified synthesis of oligoethylene glycols",

abstract = "Simple economical syntheses in good yield of octa-, nona-, and undecaethylene glycols were developed based on a coupling methodology whereby monobenzyl trior tetraethylene glycols were chain-extended either by coupling them together in the presence of tosyl chloride or through reaction with α,ω-ditosyl triethylene glycol in dioxane in the presence of powdered KOH. The α,ω-O-benzyl-protecting groups were removed by catalytic hydrogenolysis.",

keywords = "Nonaethylene glycol, Octaethylene glycol, Oligoethylene glycols, Undecaethylene glycol, α,ω-Dibenzyl oligoethylene glycols",

author = "A. Zada and Y. Avny and A. Zilkha",

year = "2001",

doi = "10.1007/s11743-001-0170-8",

language = "אנגלית",

volume = "4",

pages = "163--166",

journal = "Journal of Surfactants and Detergents",

issn = "1097-3958",

publisher = "John Wiley \& Sons Inc.",

number = "2",

}

TY - JOUR

T1 - Simplified synthesis of oligoethylene glycols

AU - Zada, A.

AU - Avny, Y.

AU - Zilkha, A.

PY - 2001

Y1 - 2001

N2 - Simple economical syntheses in good yield of octa-, nona-, and undecaethylene glycols were developed based on a coupling methodology whereby monobenzyl trior tetraethylene glycols were chain-extended either by coupling them together in the presence of tosyl chloride or through reaction with α,ω-ditosyl triethylene glycol in dioxane in the presence of powdered KOH. The α,ω-O-benzyl-protecting groups were removed by catalytic hydrogenolysis.

AB - Simple economical syntheses in good yield of octa-, nona-, and undecaethylene glycols were developed based on a coupling methodology whereby monobenzyl trior tetraethylene glycols were chain-extended either by coupling them together in the presence of tosyl chloride or through reaction with α,ω-ditosyl triethylene glycol in dioxane in the presence of powdered KOH. The α,ω-O-benzyl-protecting groups were removed by catalytic hydrogenolysis.

KW - Nonaethylene glycol

KW - Octaethylene glycol

KW - Oligoethylene glycols

KW - Undecaethylene glycol

KW - α,ω-Dibenzyl oligoethylene glycols

UR - https://www.scopus.com/pages/publications/0035654678

U2 - 10.1007/s11743-001-0170-8

DO - 10.1007/s11743-001-0170-8

M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???

AN - SCOPUS:0035654678

SN - 1097-3958

VL - 4

SP - 163

EP - 166

JO - Journal of Surfactants and Detergents

JF - Journal of Surfactants and Detergents

IS - 2

ER -

Simplified synthesis of oligoethylene glycols

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this