Sirtuin regulation in calorie restriction

Xiaolei Qiu; Katharine V. Brown; Yehu Moran; Danica Chen

doi:10.1016/j.bbapap.2009.09.015

Sirtuin regulation in calorie restriction

Xiaolei Qiu, Katharine V. Brown, Yehu Moran, Danica Chen^*

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

47 Scopus citations

Abstract

The beneficial effects of calorie restriction diet in extending lifespan and preventing diseases have long been recognized. Recent genetic and molecular studies in model organisms began to uncover the molecular regulation of calorie restriction response, with the gene SIR2 playing an essential role. This article summarizes the latest development on how mammalian SIR2 homologs coordinately regulate the calorie restriction response.

Original language	English
Pages (from-to)	1576-1583
Number of pages	8
Journal	Biochimica et Biophysica Acta - Proteins and Proteomics
Volume	1804
Issue number	8
DOIs	https://doi.org/10.1016/j.bbapap.2009.09.015
State	Published - Aug 2010
Externally published	Yes

Bibliographical note

Funding Information:
We thank Y. Liu and S. Chiao for comments and acknowledge funding support from the Searle Scholars Program to D.C.

Keywords

Aging
Calorie restriction
Sirtuin

Access to Document

10.1016/j.bbapap.2009.09.015

Cite this

@article{0575e467c4084a478309aeb9fc23bc7a,

title = "Sirtuin regulation in calorie restriction",

abstract = "The beneficial effects of calorie restriction diet in extending lifespan and preventing diseases have long been recognized. Recent genetic and molecular studies in model organisms began to uncover the molecular regulation of calorie restriction response, with the gene SIR2 playing an essential role. This article summarizes the latest development on how mammalian SIR2 homologs coordinately regulate the calorie restriction response.",

keywords = "Aging, Calorie restriction, Sirtuin",

author = "Xiaolei Qiu and Brown, {Katharine V.} and Yehu Moran and Danica Chen",

note = "Funding Information: We thank Y. Liu and S. Chiao for comments and acknowledge funding support from the Searle Scholars Program to D.C.",

year = "2010",

month = aug,

doi = "10.1016/j.bbapap.2009.09.015",

language = "אנגלית",

volume = "1804",

pages = "1576--1583",

journal = "Biochimica et Biophysica Acta - Proteins and Proteomics",

issn = "1570-9639",

publisher = "Elsevier B.V.",

number = "8",

}

TY - JOUR

T1 - Sirtuin regulation in calorie restriction

AU - Qiu, Xiaolei

AU - Brown, Katharine V.

AU - Moran, Yehu

AU - Chen, Danica

N1 - Funding Information: We thank Y. Liu and S. Chiao for comments and acknowledge funding support from the Searle Scholars Program to D.C.

PY - 2010/8

Y1 - 2010/8

N2 - The beneficial effects of calorie restriction diet in extending lifespan and preventing diseases have long been recognized. Recent genetic and molecular studies in model organisms began to uncover the molecular regulation of calorie restriction response, with the gene SIR2 playing an essential role. This article summarizes the latest development on how mammalian SIR2 homologs coordinately regulate the calorie restriction response.

AB - The beneficial effects of calorie restriction diet in extending lifespan and preventing diseases have long been recognized. Recent genetic and molecular studies in model organisms began to uncover the molecular regulation of calorie restriction response, with the gene SIR2 playing an essential role. This article summarizes the latest development on how mammalian SIR2 homologs coordinately regulate the calorie restriction response.

KW - Aging

KW - Calorie restriction

KW - Sirtuin

UR - http://www.scopus.com/inward/record.url?scp=77953293520&partnerID=8YFLogxK

U2 - 10.1016/j.bbapap.2009.09.015

DO - 10.1016/j.bbapap.2009.09.015

M3 - ???researchoutput.researchoutputtypes.contributiontojournal.systematicreview???

C2 - 19782772

AN - SCOPUS:77953293520

SN - 1570-9639

VL - 1804

SP - 1576

EP - 1583

JO - Biochimica et Biophysica Acta - Proteins and Proteomics

JF - Biochimica et Biophysica Acta - Proteins and Proteomics

IS - 8

ER -

Sirtuin regulation in calorie restriction

Abstract

Bibliographical note

Keywords

Access to Document

Other files and links

Fingerprint

Cite this