Small is mighty: EmrE, a multidrug transporter as an experimental paradigm

Shimon Schuldiner*, Dorit Granot, Sonia Steiner Mordoch, Shira Ninio, Dvir Rotem, Michael Soskin, Christopher G. Tate, Hagit Yerushalmi

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

64 Scopus citations

Abstract

EmrE is a multidrug transporter from Escherichia coli that functions as a homooligomer and is unique in its small size. In each monomer there are four tightly packed transmembrane segments and one membrane-embedded charged residue. This residue provides the basis for the coupling mechanism as part of a binding site "time shared" by substrates and protons.

Original languageAmerican English
Pages (from-to)130-134
Number of pages5
JournalNews in Physiological Sciences
Volume16
Issue number3
DOIs
StatePublished - Jun 2001

Fingerprint

Dive into the research topics of 'Small is mighty: EmrE, a multidrug transporter as an experimental paradigm'. Together they form a unique fingerprint.

Cite this