Sodium, ammonium and unilateral nephrectomy: Differential effect on microsomal ATPase of kidney cortex and medulla

H. Wald*, R. Guy, Y. Gutman, W. Czaczkes

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

1. 1. Chronic in vivo loading of rats with sodium caused increased (Na + K)-ATPase activity of 80% in the kidney medulla and 36% in the papilla. 2. 2. Unilateral nephrectomy increased (Na + K)-ATPase in the medulla by 26% and in vivo treatment with lithium caused a 76% increase in (Na + K)-ATPase of kidney medulla. 3. 3. In contrast, ammonium chloride loading caused an increase of (Na + K)-ATPase in kidney cortex (32%) and a smaller increase in medulla (12%,).

Original languageEnglish
Pages (from-to)33-37
Number of pages5
JournalInternational Journal of Biochemistry
Volume8
Issue number1
DOIs
StatePublished - 1977
Externally publishedYes

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