Sodium, ammonium and unilateral nephrectomy: Differential effect on microsomal ATPase of kidney cortex and medulla

H. Wald; R. Guy; Y. Gutman; W. Czaczkes

doi:10.1016/0020-711X(77)90125-2

Sodium, ammonium and unilateral nephrectomy: Differential effect on microsomal ATPase of kidney cortex and medulla

H. Wald^*
, R. Guy
, Y. Gutman
, W. Czaczkes

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

1. 1. Chronic in vivo loading of rats with sodium caused increased (Na + K)-ATPase activity of 80% in the kidney medulla and 36% in the papilla. 2. 2. Unilateral nephrectomy increased (Na + K)-ATPase in the medulla by 26% and in vivo treatment with lithium caused a 76% increase in (Na + K)-ATPase of kidney medulla. 3. 3. In contrast, ammonium chloride loading caused an increase of (Na + K)-ATPase in kidney cortex (32%) and a smaller increase in medulla (12%,).

Original language	English
Pages (from-to)	33-37
Number of pages	5
Journal	International Journal of Biochemistry
Volume	8
Issue number	1
DOIs	https://doi.org/10.1016/0020-711X(77)90125-2
State	Published - 1977
Externally published	Yes

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title = "Sodium, ammonium and unilateral nephrectomy: Differential effect on microsomal ATPase of kidney cortex and medulla",

abstract = "1. 1. Chronic in vivo loading of rats with sodium caused increased (Na + K)-ATPase activity of 80\% in the kidney medulla and 36\% in the papilla. 2. 2. Unilateral nephrectomy increased (Na + K)-ATPase in the medulla by 26\% and in vivo treatment with lithium caused a 76\% increase in (Na + K)-ATPase of kidney medulla. 3. 3. In contrast, ammonium chloride loading caused an increase of (Na + K)-ATPase in kidney cortex (32\%) and a smaller increase in medulla (12\%,).",

author = "H. Wald and R. Guy and Y. Gutman and W. Czaczkes",

year = "1977",

doi = "10.1016/0020-711X(77)90125-2",

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AU - Wald, H.

AU - Guy, R.

AU - Gutman, Y.

AU - Czaczkes, W.

PY - 1977

Y1 - 1977

N2 - 1. 1. Chronic in vivo loading of rats with sodium caused increased (Na + K)-ATPase activity of 80% in the kidney medulla and 36% in the papilla. 2. 2. Unilateral nephrectomy increased (Na + K)-ATPase in the medulla by 26% and in vivo treatment with lithium caused a 76% increase in (Na + K)-ATPase of kidney medulla. 3. 3. In contrast, ammonium chloride loading caused an increase of (Na + K)-ATPase in kidney cortex (32%) and a smaller increase in medulla (12%,).

AB - 1. 1. Chronic in vivo loading of rats with sodium caused increased (Na + K)-ATPase activity of 80% in the kidney medulla and 36% in the papilla. 2. 2. Unilateral nephrectomy increased (Na + K)-ATPase in the medulla by 26% and in vivo treatment with lithium caused a 76% increase in (Na + K)-ATPase of kidney medulla. 3. 3. In contrast, ammonium chloride loading caused an increase of (Na + K)-ATPase in kidney cortex (32%) and a smaller increase in medulla (12%,).

UR - https://www.scopus.com/pages/publications/0017344830

U2 - 10.1016/0020-711X(77)90125-2

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EP - 37

JO - International Journal of Biochemistry

JF - International Journal of Biochemistry

IS - 1

ER -

Sodium, ammonium and unilateral nephrectomy: Differential effect on microsomal ATPase of kidney cortex and medulla

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