Somatic rearrangements across cancer reveal classes of samples with distinct patterns of DNA breakage and rearrangement-induced hypermutability

Keyphrases

• Hypermutability 100%
• Somatic Rearrangement 100%
• DNA Breakage 100%
• Distinct Patterns 100%
• DNA Rearrangement 100%
• Tumor Subtype 66%
• Microhomology 66%
• In Cancer 33%
• Germ Cells 33%
• GC Content 33%
• Whole Genome Sequencing 33%
• Multiple Myeloma 33%
• Transcription Rate 33%
• Prostate Carcinoma 33%
• Multiple Chronic Conditions 33%
• Massively Parallel Sequencing 33%
• Tumor Genome 33%
• Genomic Location 33%
• Genome Sequencing 33%
• Breast 33%
• Detection Accuracy 33%
• Sequencing Technology 33%
• Melanoma 33%
• Transversion 33%
• Replication Time 33%
• Chronic Lymphocytic Leukemia 33%
• APC Gene 33%
• Head-and-neck Squamous Cell Carcinoma (HNSCC) 33%
• Colorectal Carcinoma 33%

Biochemistry, Genetics and Molecular Biology

• Genomics 100%
• Transcription 50%
• Germline 50%
• Germ Cell 50%
• Deep Sequencing 50%
• GC-content 50%
• Whole Genome Sequencing 50%
• Transversion 50%