Specific lymphocyte transformation in murine malaria

J. Golenser; D. T. Spira; J. P. Verhave; J. H.E.Th Meuwissen

doi:10.1007/BF00389938

Specific lymphocyte transformation in murine malaria

J. Golenser^*, D. T. Spira, J. P. Verhave, J. H.E.Th Meuwissen

^*Corresponding author for this work

Institute for Medical Research Israel-Canada (IMRIC)

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Lymphoblast transformation tests were performed on convalescent rats and mice, after infection with Plasmodium berghei had been reduced to latency. Spleen cells from immune animals reacted in vitro to specific plasmodial antigen and not to control antigen produced from non infected RBC. The response in vitro was dependent on the concentration of the antigen and the time of exposure to it. A correlation was observed between the parasitaemia of the convalescent animal during its acute infection and the reaction in vitro: the higher the parasitaemia the higher the in vitro stimulation.

Original language	English
Pages (from-to)	95-98
Number of pages	4
Journal	Parasitology Research
Volume	50
Issue number	1
DOIs	https://doi.org/10.1007/BF00389938
State	Published - Jan 1976

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abstract = "Lymphoblast transformation tests were performed on convalescent rats and mice, after infection with Plasmodium berghei had been reduced to latency. Spleen cells from immune animals reacted in vitro to specific plasmodial antigen and not to control antigen produced from non infected RBC. The response in vitro was dependent on the concentration of the antigen and the time of exposure to it. A correlation was observed between the parasitaemia of the convalescent animal during its acute infection and the reaction in vitro: the higher the parasitaemia the higher the in vitro stimulation.",

author = "J. Golenser and Spira, {D. T.} and Verhave, {J. P.} and Meuwissen, {J. H.E.Th}",

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Specific lymphocyte transformation in murine malaria

Abstract

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