SQSTM1/p62-mediated autophagy compensates for loss of proteasome polyubiquitin recruiting capacity

Keyphrases

• Autophagy 100%
• Polyubiquitin 100%
• SQSTM1 100%
• Transcription Factor 25%
• Steady State 25%
• Physiological Condition 25%
• Macroautophagy 25%
• Eukaryotic Cells 25%
• Cargo 25%
• Knockdown 25%
• Protein Homeostasis 25%
• Molecular Mechanism 25%
• Autophagosome 25%
• Ubiquitin-proteasome System 25%
• Overflow 25%
• Sequestration 25%
• Cellular Models 25%
• Polyubiquitinated Proteins 25%
• Activating Transcription Factor 4 (ATF4) 25%
• Substrate Accumulation 25%
• Degradation Pathway 25%
• Ubiquitin Receptor 25%
• Molecular Crosstalk 25%
• Phagophore 25%
• PSMD4 25%
• Proteostatic Stress 25%
• Proteasomal Inhibition 25%
• ADRM1 25%
• Autophagic Pathway 25%
• Selective Autophagy 25%
• Aggregate Formation 25%

Biochemistry, Genetics and Molecular Biology

• Autophagy 100%
• Proteasome 100%
• Ubiquitin 100%
• Transcription Factors 50%
• Precursor 50%
• Macroautophagy 50%
• Steady State 50%
• Protein Homeostasis 50%
• Upregulation 50%
• Autophagosome 50%
• ATF4 50%
• Selective Autophagy 50%