Stereospecific oxidation by Compound I of Cytochrome P450 does not proceed in a concerted synchronous manner

Sam P. de Visser; François Ogliaro; Sason Shaik

doi:10.1039/b105571m

Stereospecific oxidation by Compound I of Cytochrome P450 does not proceed in a concerted synchronous manner

Sam P. de Visser, François Ogliaro, Sason Shaik^*

^*Corresponding author for this work

Institute of Chemistry

Research output: Contribution to journal › Article › peer-review

39 Scopus citations

Abstract

Calculations show that the transition structure for the synchronous oxygen transfer by Compound I is a second order saddle point. The process is unlikely.

Original language	English
Pages (from-to)	2322-2323
Number of pages	2
Journal	Chemical Communications
Volume	1
Issue number	22
DOIs	https://doi.org/10.1039/b105571m
State	Published - 2001

Access to Document

10.1039/b105571m

Cite this

@article{f43a66b2f8b144c6baceb66b19601b28,

title = "Stereospecific oxidation by Compound I of Cytochrome P450 does not proceed in a concerted synchronous manner",

abstract = "Calculations show that the transition structure for the synchronous oxygen transfer by Compound I is a second order saddle point. The process is unlikely.",

author = "{de Visser}, {Sam P.} and Fran{\c c}ois Ogliaro and Sason Shaik",

year = "2001",

doi = "10.1039/b105571m",

language = "אנגלית",

volume = "1",

pages = "2322--2323",

journal = "Chemical Communications",

issn = "1359-7345",

publisher = "Royal Society of Chemistry",

number = "22",

}

TY - JOUR

T1 - Stereospecific oxidation by Compound I of Cytochrome P450 does not proceed in a concerted synchronous manner

AU - de Visser, Sam P.

AU - Ogliaro, François

AU - Shaik, Sason

PY - 2001

Y1 - 2001

N2 - Calculations show that the transition structure for the synchronous oxygen transfer by Compound I is a second order saddle point. The process is unlikely.

AB - Calculations show that the transition structure for the synchronous oxygen transfer by Compound I is a second order saddle point. The process is unlikely.

UR - http://www.scopus.com/inward/record.url?scp=0035929953&partnerID=8YFLogxK

U2 - 10.1039/b105571m

DO - 10.1039/b105571m

M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???

C2 - 12240056

AN - SCOPUS:0035929953

SN - 1359-7345

VL - 1

SP - 2322

EP - 2323

JO - Chemical Communications

JF - Chemical Communications

IS - 22

ER -

Stereospecific oxidation by Compound I of Cytochrome P450 does not proceed in a concerted synchronous manner

Abstract

Access to Document

Other files and links

Fingerprint

Cite this