Structure of T4 Pyrimidine Dimer Glycosylase in a Reduced Imine Covalent Complex with Abasic Site-containing DNA

Keyphrases

• Cyclobutane Pyrimidine Dimers 100%
• Glycoside Hydrolase 100%
• Abasic Site 100%
• Imines 100%
• Covalent Complex 100%
• Co-crystal Structure 33%
• Cross-linked 16%
• Active Sites 16%
• Pyrimidine 16%
• Light-induced 16%
• Incubation 16%
• High-resolution Structures 16%
• Catalytic Reaction 16%
• Incompetence 16%
• Structural Requirements 16%
• Oligodeoxynucleotide 16%
• Chemical Reaction 16%
• Key Amino Acids 16%
• Kink 16%
• Protein-DNA Complex 16%
• Threonine 16%
• Duplex 16%
• Reducing Agent 16%
• DNA Substrates 16%
• Covalent Bond 16%
• Lyase 16%
• Amino Group 16%
• DNA Glycosylase 16%
• Phosphodiester Bond 16%
• Cyclobutane Dimer 16%
• Glycosyl 16%
• Catalytic Characteristics 16%
• Deoxyribose 16%
• Base Excision Repair Pathway 16%
• Nucleotide Flipping 16%
• Covalent Intermediate 16%
• Trapping Reactions 16%
• Bond Scission 16%
• DNA Bending 16%

Biochemistry, Genetics and Molecular Biology

• Pyrimidine Dimer 100%
• Glycosylase 100%
• Enzyme 33%
• Crystal Structure 33%
• Amino Acids 16%
• N-Terminus 16%
• Base Excision Repair 16%
• Active Site 16%
• Glycosyl 16%
• DNA Protein Complex 16%
• Catalysis 16%
• DNA Glycosylase 16%
• Phosphodiester Bond 16%
• Covalent Bond 16%
• Deoxyribose 16%
• Lyase 16%
• DNA Bending 16%
• Threonine 16%