Abstract
Syntheses are described of a series of peptides and peptide derivatives which correspond to the sequence of the seven N-terminal positions in the primary structure of bovine pancreatic ribonuclease A. The hydrazides of Nα,Nω-di-t-butyloxycarbonyllysyl-γ-t-butylglutamyl-threonylalanylalanylalanyl-Nω-t-but yloxycarbonylly sine, N-t-butyloxycarbonylthreonylalanylalanylalanyl-Nω-t-butyloxycarbonyllysine, and t-butyloxycarbonylalanyl-alanylalanyl-Nω-t-butyloxycarbonyllysine whose preparation is described served to introduce the N-terminal section into more complex peptides related to ribonuclease.
Original language | English |
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Pages (from-to) | 611-619 |
Number of pages | 9 |
Journal | Journal of the American Chemical Society |
Volume | 87 |
Issue number | 3 |
DOIs | |
State | Published - 1965 |
Externally published | Yes |