Studies on Polypeptides. XXXII. Synthetic Peptides Related to the N-Terminus of Bovine Pancreatic Ribonuclease A (Positions 1-13)1-4

Klaus Hofmann; Ralph Schmiechen; Michael J. Smithers; Robert D. Wells; Yecheskel Wolman; Guido Zanetti

doi:10.1021/ja01081a042

Studies on Polypeptides. XXXII. Synthetic Peptides Related to the N-Terminus of Bovine Pancreatic Ribonuclease A (Positions 1-13)^1-4

Klaus Hofmann
, Ralph Schmiechen
, Michael J. Smithers
, Robert D. Wells
, Yecheskel Wolman
, Guido Zanetti

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Syntheses are described of the following seven peptides all related to the N-terminus of bovine pancreatic ribonuclease A: Nʹ-formyllysylphenylalanylglutamyl-arginylglutaminylhistidylmethionine, alanylalanylqlanyl-lysylphenylalanylglutamylargin ylglutaminylhist idy l-methionine, threonylalanylalanylalanylly s ylphenyl-alanylglutamylarginylglutaminylhistidylmethionine, ly-sylglutamylthreonylala ny lalanyla lan ylly sylph en yl-alanylglutamylarginylglutamine, lysylglutamylthreonyl-alanylalanylalanyllysylphenylala nylglutamylarginyl-glutaminylhistidine amide, lysylglutamylthreonylalanyl-alanylalanyllysylglutamylargin ylglutaminylhist idy l-methionine, and lysylglutamylthreonylalanylalanyl-alanyllysylphenylalanylgl utam ylarginylglutaminyl-histidyl-a-amino-n-butyric acid. Evidence is presented for the homogeneity of these compounds.

Original language	English
Pages (from-to)	640-644
Number of pages	5
Journal	Journal of the American Chemical Society
Volume	87
Issue number	3
DOIs	https://doi.org/10.1021/ja01081a042
State	Published - 1965
Externally published	Yes

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@article{1c3dbfd66a4148ee9dc964b87388a607,

title = "Studies on Polypeptides. XXXII. Synthetic Peptides Related to the N-Terminus of Bovine Pancreatic Ribonuclease A (Positions 1-13)1-4",

abstract = "Syntheses are described of the following seven peptides all related to the N-terminus of bovine pancreatic ribonuclease A: Nʹ-formyllysylphenylalanylglutamyl-arginylglutaminylhistidylmethionine, alanylalanylqlanyl-lysylphenylalanylglutamylargin ylglutaminylhist idy l-methionine, threonylalanylalanylalanylly s ylphenyl-alanylglutamylarginylglutaminylhistidylmethionine, ly-sylglutamylthreonylala ny lalanyla lan ylly sylph en yl-alanylglutamylarginylglutamine, lysylglutamylthreonyl-alanylalanylalanyllysylphenylala nylglutamylarginyl-glutaminylhistidine amide, lysylglutamylthreonylalanyl-alanylalanyllysylglutamylargin ylglutaminylhist idy l-methionine, and lysylglutamylthreonylalanylalanyl-alanyllysylphenylalanylgl utam ylarginylglutaminyl-histidyl-a-amino-n-butyric acid. Evidence is presented for the homogeneity of these compounds.",

author = "Klaus Hofmann and Ralph Schmiechen and Smithers, \{Michael J.\} and Wells, \{Robert D.\} and Yecheskel Wolman and Guido Zanetti",

year = "1965",

doi = "10.1021/ja01081a042",

language = "אנגלית",

volume = "87",

pages = "640--644",

journal = "Journal of the American Chemical Society",

issn = "0002-7863",

publisher = "American Chemical Society",

number = "3",

}

TY - JOUR

T1 - Studies on Polypeptides. XXXII. Synthetic Peptides Related to the N-Terminus of Bovine Pancreatic Ribonuclease A (Positions 1-13)1-4

AU - Hofmann, Klaus

AU - Schmiechen, Ralph

AU - Smithers, Michael J.

AU - Wells, Robert D.

AU - Wolman, Yecheskel

AU - Zanetti, Guido

PY - 1965

Y1 - 1965

N2 - Syntheses are described of the following seven peptides all related to the N-terminus of bovine pancreatic ribonuclease A: Nʹ-formyllysylphenylalanylglutamyl-arginylglutaminylhistidylmethionine, alanylalanylqlanyl-lysylphenylalanylglutamylargin ylglutaminylhist idy l-methionine, threonylalanylalanylalanylly s ylphenyl-alanylglutamylarginylglutaminylhistidylmethionine, ly-sylglutamylthreonylala ny lalanyla lan ylly sylph en yl-alanylglutamylarginylglutamine, lysylglutamylthreonyl-alanylalanylalanyllysylphenylala nylglutamylarginyl-glutaminylhistidine amide, lysylglutamylthreonylalanyl-alanylalanyllysylglutamylargin ylglutaminylhist idy l-methionine, and lysylglutamylthreonylalanylalanyl-alanyllysylphenylalanylgl utam ylarginylglutaminyl-histidyl-a-amino-n-butyric acid. Evidence is presented for the homogeneity of these compounds.

AB - Syntheses are described of the following seven peptides all related to the N-terminus of bovine pancreatic ribonuclease A: Nʹ-formyllysylphenylalanylglutamyl-arginylglutaminylhistidylmethionine, alanylalanylqlanyl-lysylphenylalanylglutamylargin ylglutaminylhist idy l-methionine, threonylalanylalanylalanylly s ylphenyl-alanylglutamylarginylglutaminylhistidylmethionine, ly-sylglutamylthreonylala ny lalanyla lan ylly sylph en yl-alanylglutamylarginylglutamine, lysylglutamylthreonyl-alanylalanylalanyllysylphenylala nylglutamylarginyl-glutaminylhistidine amide, lysylglutamylthreonylalanyl-alanylalanyllysylglutamylargin ylglutaminylhist idy l-methionine, and lysylglutamylthreonylalanylalanyl-alanyllysylphenylalanylgl utam ylarginylglutaminyl-histidyl-a-amino-n-butyric acid. Evidence is presented for the homogeneity of these compounds.

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DO - 10.1021/ja01081a042

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C2 - 14263389

AN - SCOPUS:33947482174

SN - 0002-7863

VL - 87

SP - 640

EP - 644

JO - Journal of the American Chemical Society

JF - Journal of the American Chemical Society

IS - 3

ER -

Studies on Polypeptides. XXXII. Synthetic Peptides Related to the N-Terminus of Bovine Pancreatic Ribonuclease A (Positions 1-13)^1-4

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