TY - JOUR
T1 - Studies on Potential Antiviral Compounds, XXIV. New 1‐substituted isatin β‐thiosemicarbazones
AU - Ferranti, Anna
AU - Garuti, Laura
AU - Giovanninetti, Giuseppe
AU - Katz, Ehud
PY - 1985
Y1 - 1985
N2 - Some new 1‐substituted isatin β‐thiosemicarbazones were examined for their ability to inhibit the growth of the wild‐type strain of vaccinia virus and the isatin P‐thiosemicarbazone (IBT) resistant mutant of this virus. Also investigated was the capability of the compounds to support the growth of the IBT dependent mutant of vaccinia virus. The most active derivative is 1‐(3‐hydroxypropyl)isatin thiosemicarbazone 20, which was shown to be more effective than IBT.
AB - Some new 1‐substituted isatin β‐thiosemicarbazones were examined for their ability to inhibit the growth of the wild‐type strain of vaccinia virus and the isatin P‐thiosemicarbazone (IBT) resistant mutant of this virus. Also investigated was the capability of the compounds to support the growth of the IBT dependent mutant of vaccinia virus. The most active derivative is 1‐(3‐hydroxypropyl)isatin thiosemicarbazone 20, which was shown to be more effective than IBT.
UR - http://www.scopus.com/inward/record.url?scp=0021807138&partnerID=8YFLogxK
U2 - 10.1002/ardp.19853180507
DO - 10.1002/ardp.19853180507
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C2 - 4026537
AN - SCOPUS:0021807138
SN - 0365-6233
VL - 318
SP - 415
EP - 421
JO - Archiv der Pharmazie
JF - Archiv der Pharmazie
IS - 5
ER -