Studying Plaque Biofilms on Various Dental Surfaces

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review


Oral biofilms harboring pathogenic bacteria, are the major contributing virulent factors associated with diseases of the oral cavity, such as tooth decay, gingivitis and periodontitis. In addition to the virulent properties of the biofilm, adhesion to oral surfaces is a key factor in the survival of bacteria in the oral cavity. Bacteria that are not part of a biofilm are ordinarily flushed out of the oral cavity. The dental biofilm is not only a site harboring oral bacteria, but may serve as a protective environment for the embedded microorganisms. Within the biofilm ecosystem, microorganisms are less susceptible to antibacterial agents, and are better protected from the host defense system. It is also conceivable that bacteria in the biofilm exhibit different phenotypic and genotypic characteristics than do planktonic bacteria. In addition, cell-free proteins and enzymes may differ in their characteristics and activity, probably due to conformational changes upon being immobilized on the surface, and due to local conditions in the biofilm environment.
Original languageAmerican English
Title of host publicationHandbook of Bacterial Adhesion
Subtitle of host publicationPrinciples, Methods, and Applications
EditorsYuehuei H. An, Richard J. Friedman
Place of PublicationTotowa, NJ
PublisherHumana Press
Number of pages18
ISBN (Electronic)978-1-59259-224-1
ISBN (Print)978-1-61737-192-9
StatePublished - 2000

Bibliographical note

644 pages


  • Oral biofilms
  • Plaque Biofilms
  • bacteria
  • oral cavity


Dive into the research topics of 'Studying Plaque Biofilms on Various Dental Surfaces'. Together they form a unique fingerprint.

Cite this