Subcutaneous, omentum and tumor fatty acid composition, and serum insulin status in patients with benign or cancerous ovarian or endometrial tumors. Do tumors preferentially utilize polyunsaturated fatty acids?

D. Yam*, H. Ben-Hur, R. Dgani, A. Fink, A. Shani, E. M. Berry

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

The relationships between the fatty acid composition of cancerous endometrium and ovary, and peripheral adipose tissues were studied in Israeli Jewish women, and are presented together since no differences were shown between them. The results suggest a mobilization of linoleic acid from subcutaneous and omental depots and its incorporation into tumors accompanied by a high degree of desaturation. High blood insulin concentrations characterized patients with stage I and II disease, and low concentrations characterized patients with advanced degrees of malignancy.

Original languageEnglish
Pages (from-to)179-185
Number of pages7
JournalCancer Letters
Volume111
Issue number1-2
DOIs
StatePublished - 1 Jan 1997

Keywords

  • Cancer
  • Fatty acid composition
  • Serum insulin

Fingerprint

Dive into the research topics of 'Subcutaneous, omentum and tumor fatty acid composition, and serum insulin status in patients with benign or cancerous ovarian or endometrial tumors. Do tumors preferentially utilize polyunsaturated fatty acids?'. Together they form a unique fingerprint.

Cite this