Abstract
A patient who had 3 first‐trimester spontaneous abortions (blighted ova) was found to be carrying a balanced 13/14 Robertsonian translocation. In the 2 cases cytogenetically analyzed, different chromosomal aberrations were found (trisomy 16 and supernumerary D elements). Histologic examination of the placentas of all 3 abortions revealed hypovascular or avas‐cular villi, hydropic degeneration, and occasional atypical stromal (Hofbaucr‐like) cells. In 2 cases the decidua was examined by light microscopy and was diffusely inflamed with a plasmolymphocytic infiltrate. The relation of the maternal translocation to the repeated abortions with chromosome anomalies is discussed.
| Original language | English |
|---|---|
| Pages (from-to) | 283-289 |
| Number of pages | 7 |
| Journal | Teratology |
| Volume | 12 |
| Issue number | 3 |
| DOIs | |
| State | Published - Dec 1975 |
| Externally published | Yes |
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