Sugar metabolism in the extremely halophilic bacterium Salinibacter ruber

Aharon Oren*, Lili Mana

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

23 Scopus citations

Abstract

Growth of Salinibacter ruber, a red, extremely halophilic bacterium phylogenetically affiliated with the Flavobacterium/Cytophaga branch of the domain Bacteria, is stimulated by a small number of sugars (glucose, maltose, starch at 1 g l-1). Glucose consumption starts after other substrates have been depleted. Glucose metabolism proceeds via a constitutive, salt-inhibited hexokinase and a constitutive salt-dependent nicotinamide adenine dinucleotide phosphate (NADP)-linked glucose-6-phosphate dehydrogenase. Glucose dehydrogenase and fructose-1,6-bisphosphate aldolase activity could not be detected. It is therefore suggested that Salinibacter metabolizes glucose by the classic Entner-Doudoroff pathway and not by the Embden-Meyerhof glycolytic pathway or by the modified Entner-Doudoroff pathway present in halophilic Archaea of the family Halobacteriaceae, in which the phosphorylation step is postponed. However, activity of 2-keto-3-deoxy-6-phosphogluconate aldolase could not be detected in extracts of Salinibacter cells, whether or not grown in the presence of glucose.

Original languageAmerican English
Pages (from-to)83-87
Number of pages5
JournalFEMS Microbiology Letters
Volume223
Issue number1
DOIs
StatePublished - 6 Jun 2003

Bibliographical note

Funding Information:
This study was supported by a grant from the Israel Science Foundation founded by the Israel Academy of Sciences and Humanities.

Keywords

  • 2-Keto-3-deoxy-6-phosphogluconate aldolase
  • Entner-Doudoroff pathway
  • Fructose-1,6-bisphosphate aldolase
  • Glucose
  • Glucose-6-phosphate dehydrogenase
  • Hexokinase
  • Salinibacter ruber

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