Abstract
An Epstein-Barr virus (EBV) related herpes virus H. papio (HVP) derived from 9B cell line was shown to inhibit the DNA synthesis in B-cell mitogen stimulated human lymphocytes, in B95-8 virus exposed human lymphocytes, and the DNA metabolism of EBV-receptor positive cell lines. The inhibition could be abolished by a Burkitt serum known to have a high anti-EBV titer. Similar inhibition activities were shown for P3HR-1 virus. The relationship between the inability to immortalize normal cells, the ability to induce early antigen (EA) in certain cell lines and the DNA inhibitory effect of both 9B and P3HR-1 viruses is discussed.
| Original language | English |
|---|---|
| Pages (from-to) | 217-222 |
| Number of pages | 6 |
| Journal | European Journal of Cancer (1965) |
| Volume | 15 |
| Issue number | 2 |
| DOIs | |
| State | Published - Feb 1979 |
| Externally published | Yes |
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SDG 3 Good Health and Well-being
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