TY - JOUR
T1 - Superoxide production during refeeding in patients with anorexia nervosa
AU - Vaisman, Nachum
AU - Tabachnik, Elvan
AU - Hahn, Talia
AU - Voet, Hillary
AU - Guy, Nina
PY - 1992/10
Y1 - 1992/10
N2 - The effect of undernutrition and refeeding on superoxide production by polymorphonuclear cells (PMN) was studied in 11 girls suffering from anorexia nervosa (AN) and 17 age-matched, normal, healthy, control subjects. Superoxide anion production by PMNs from undernourished AN patients was comparable to normal, while a significant decrease in this function was observed during the initial period of refeeding. After a more extended period of refeeding, superoxide production by PMNs from AN patients increased and gradually returned toward normal values. Superoxide production correlated with length of the refeeding period (RF), weight as a percentage of ideal weight for height ( W H%), and rate of weight gain (WG). These results imply that a variety of physiological parameters, including susceptibility to infection, may be altered by refeeding undernourished patients.
AB - The effect of undernutrition and refeeding on superoxide production by polymorphonuclear cells (PMN) was studied in 11 girls suffering from anorexia nervosa (AN) and 17 age-matched, normal, healthy, control subjects. Superoxide anion production by PMNs from undernourished AN patients was comparable to normal, while a significant decrease in this function was observed during the initial period of refeeding. After a more extended period of refeeding, superoxide production by PMNs from AN patients increased and gradually returned toward normal values. Superoxide production correlated with length of the refeeding period (RF), weight as a percentage of ideal weight for height ( W H%), and rate of weight gain (WG). These results imply that a variety of physiological parameters, including susceptibility to infection, may be altered by refeeding undernourished patients.
UR - http://www.scopus.com/inward/record.url?scp=0026649267&partnerID=8YFLogxK
U2 - 10.1016/0026-0495(92)90292-I
DO - 10.1016/0026-0495(92)90292-I
M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???
C2 - 1328821
AN - SCOPUS:0026649267
SN - 0026-0495
VL - 41
SP - 1097
EP - 1099
JO - Metabolism: Clinical and Experimental
JF - Metabolism: Clinical and Experimental
IS - 10
ER -