Surface reaction of Leishmania: II. Correlation between surface antigens and mixed serotypes

R. L. Jacobson, L. F. Schnur, G. M. Slutzky, C. L. Greenblatt, J. J. Doyle

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Leishmanial strains of mixed AB serotypes were tested by immunofluorescent techniques to determine if they comprise mixed populations of A and B organisms or whether each parasite carries both antigenic determinants. The strains used were classified as A1B2, A2B2, A3B2 and A4B2 by the behaviour of their excreted factor (EF) in double gel diffusion tests against standard A and B rabbit antisera. The results showed that all organisms of an AB strain were labelled with both fluorescent anti-A and anti-B sera and that such a population could be differentiated from an artificial mixture of A and B strains.

Original languageEnglish
Pages (from-to)521-525
Number of pages5
JournalAnnals of Tropical Medicine and Parasitology
Volume76
Issue number5
DOIs
StatePublished - Oct 1982

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