Sweet Killers: NK Cells Need Glycolysis to Kill Tumors

Batya Isaacson; Ofer Mandelboim

doi:10.1016/j.cmet.2018.07.008

Sweet Killers: NK Cells Need Glycolysis to Kill Tumors

Batya Isaacson
, Ofer Mandelboim^*

^*Corresponding author for this work

Department of Immunology and Cancer Research

Research output: Contribution to journal › Short survey › peer-review

23 Scopus citations

Abstract

Natural killer (NK) cells are cytotoxic innate lymphocytes that play a major role in the immune battle against cancer. In this issue of Cell Metabolism, Cong et al. (2018) demonstrate that progressing tumors reduce NK cell glycolytic capacity, which leads to reduced cytotoxicity and an overall dysfunctional NK phenotype. Natural killer (NK) cells are cytotoxic innate lymphocytes that play a major role in the immune battle against cancer. In this issue of Cell Metabolism, Cong et al. (2018) demonstrate that progressing tumors reduce NK cell glycolytic capacity, which leads to reduced cytotoxicity and an overall dysfunctional NK phenotype.

Original language	English
Pages (from-to)	183-184
Number of pages	2
Journal	Cell Metabolism
Volume	28
Issue number	2
DOIs	https://doi.org/10.1016/j.cmet.2018.07.008
State	Published - 7 Aug 2018

Bibliographical note

Publisher Copyright:
© 2018 Elsevier Inc.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Access to Document

10.1016/j.cmet.2018.07.008

Cite this

@article{a9452340ac5a455a93a9f17ffea228cb,

title = "Sweet Killers: NK Cells Need Glycolysis to Kill Tumors",

abstract = "Natural killer (NK) cells are cytotoxic innate lymphocytes that play a major role in the immune battle against cancer. In this issue of Cell Metabolism, Cong et al. (2018) demonstrate that progressing tumors reduce NK cell glycolytic capacity, which leads to reduced cytotoxicity and an overall dysfunctional NK phenotype. Natural killer (NK) cells are cytotoxic innate lymphocytes that play a major role in the immune battle against cancer. In this issue of Cell Metabolism, Cong et al. (2018) demonstrate that progressing tumors reduce NK cell glycolytic capacity, which leads to reduced cytotoxicity and an overall dysfunctional NK phenotype.",

author = "Batya Isaacson and Ofer Mandelboim",

note = "Publisher Copyright: {\textcopyright} 2018 Elsevier Inc.",

year = "2018",

month = aug,

day = "7",

doi = "10.1016/j.cmet.2018.07.008",

language = "אנגלית",

volume = "28",

pages = "183--184",

journal = "Cell Metabolism",

issn = "1550-4131",

publisher = "Cell Press",

number = "2",

}

TY - JOUR

T1 - Sweet Killers

T2 - NK Cells Need Glycolysis to Kill Tumors

AU - Isaacson, Batya

AU - Mandelboim, Ofer

PY - 2018/8/7

Y1 - 2018/8/7

N2 - Natural killer (NK) cells are cytotoxic innate lymphocytes that play a major role in the immune battle against cancer. In this issue of Cell Metabolism, Cong et al. (2018) demonstrate that progressing tumors reduce NK cell glycolytic capacity, which leads to reduced cytotoxicity and an overall dysfunctional NK phenotype. Natural killer (NK) cells are cytotoxic innate lymphocytes that play a major role in the immune battle against cancer. In this issue of Cell Metabolism, Cong et al. (2018) demonstrate that progressing tumors reduce NK cell glycolytic capacity, which leads to reduced cytotoxicity and an overall dysfunctional NK phenotype.

AB - Natural killer (NK) cells are cytotoxic innate lymphocytes that play a major role in the immune battle against cancer. In this issue of Cell Metabolism, Cong et al. (2018) demonstrate that progressing tumors reduce NK cell glycolytic capacity, which leads to reduced cytotoxicity and an overall dysfunctional NK phenotype. Natural killer (NK) cells are cytotoxic innate lymphocytes that play a major role in the immune battle against cancer. In this issue of Cell Metabolism, Cong et al. (2018) demonstrate that progressing tumors reduce NK cell glycolytic capacity, which leads to reduced cytotoxicity and an overall dysfunctional NK phenotype.

UR - https://www.scopus.com/pages/publications/85050277093

U2 - 10.1016/j.cmet.2018.07.008

DO - 10.1016/j.cmet.2018.07.008

M3 - ???researchoutput.researchoutputtypes.contributiontojournal.shortsurvey???

AN - SCOPUS:85050277093

SN - 1550-4131

VL - 28

SP - 183

EP - 184

JO - Cell Metabolism

JF - Cell Metabolism

IS - 2

ER -

Sweet Killers: NK Cells Need Glycolysis to Kill Tumors

Abstract

Bibliographical note

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this