Abstract
DNA nanostructures acting as DNA machines are described. Specifically, DNA "walkers" assembled on nucleic acid scaffolds and triggered by fuel/antifuel strands are activated in solution or on surfaces, for example, electrodes or semiconductor CdSe/ZnS quantum dots (QDs). The DNA machines led to the switchable formation or dissociation of the hemin/G-quadruplex DNAzyme on the DNA scaffolds. This enabled the chemiluminescence, chemiluminescence resonance energy transfer (CRET), electrochemical, or photoelectrochemical transduction of the switchable states of the different DNA machines.
Original language | English |
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Pages (from-to) | 219-225 |
Number of pages | 7 |
Journal | Nano Letters |
Volume | 13 |
Issue number | 1 |
DOIs | |
State | Published - 9 Jan 2013 |
Keywords
- chemiluminescence
- DNA
- machine
- nanotechnology
- quantum dots (QDs)
- walker