Synaptogenesis and myelination in dissociated cerebral microcarrier cell cultures

A. Shahar; S. Reuveny; A. Amir; M. Kotler; A. Mizrahi

doi:10.1002/jnr.490090310

Synaptogenesis and myelination in dissociated cerebral microcarrier cell cultures

A. Shahar^*
, S. Reuveny
, A. Amir
, M. Kotler
, A. Mizrahi

^*Corresponding author for this work

Institute for Medical Research Israel-Canada (IMRIC)

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

A new approach for cultivating dissociated cerebral neurons is described. It is based on a rapid attachment of neurons to the DEAE‐cellulose cylindrical MC and their subsequent interconnection to form cell‐MC conglomerates. Intensive fiber growth followed by synaptogenesis and progressive myelin formation are indicative of optimal conditions of nutrition and oxygenation.

Original language	English
Pages (from-to)	339-348
Number of pages	10
Journal	Journal of Neuroscience Research
Volume	9
Issue number	3
DOIs	https://doi.org/10.1002/jnr.490090310
State	Published - 1983

Keywords

conglomerates
microcarriers
myelin
neurons
synapses

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10.1002/jnr.490090310

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abstract = "A new approach for cultivating dissociated cerebral neurons is described. It is based on a rapid attachment of neurons to the DEAE‐cellulose cylindrical MC and their subsequent interconnection to form cell‐MC conglomerates. Intensive fiber growth followed by synaptogenesis and progressive myelin formation are indicative of optimal conditions of nutrition and oxygenation.",

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AU - Reuveny, S.

AU - Amir, A.

AU - Kotler, M.

AU - Mizrahi, A.

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AB - A new approach for cultivating dissociated cerebral neurons is described. It is based on a rapid attachment of neurons to the DEAE‐cellulose cylindrical MC and their subsequent interconnection to form cell‐MC conglomerates. Intensive fiber growth followed by synaptogenesis and progressive myelin formation are indicative of optimal conditions of nutrition and oxygenation.

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KW - microcarriers

KW - myelin

KW - neurons

KW - synapses

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Synaptogenesis and myelination in dissociated cerebral microcarrier cell cultures

Abstract

Keywords

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