Synchronization of Plasmodium yoelii nigeriensis and P. y. killicki infection in the mouse by means of Percoll-glucose gradient stage fractionation: Determination of the duration of the schizogonic cycle

Eric Deharo, Philippe Gautret, Hagaï Ginsburg, Alain Gabriel Chabaud, Irène Landau*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

32 Scopus citations

Abstract

The youngest (rings and young trophozoites) erythrocytic stages of Plasmodium yoelii nigeriensis and P. yoelii killicki, two rodent malaria subspecies developing very asynchronously in the blood, were separated from the other stages using a discontinuous Percoll-glucose gradient. They were inoculated into mice and the subsequent infection remained synchronous for two generations. The duration of the asexual cycle was found to be 18 h.

Original languageEnglish
Pages (from-to)159-164
Number of pages6
JournalParasitology Research
Volume80
Issue number2
DOIs
StatePublished - Feb 1994

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