TY - JOUR
T1 - Synchronization with mismatched synaptic delays
T2 - A unique role of elastic neuronal latency
AU - Vardi, R.
AU - Timor, R.
AU - Marom, S.
AU - Abeles, M.
AU - Kanter, I.
PY - 2012/12
Y1 - 2012/12
N2 - We show that the unavoidable increase in neuronal response latency to ongoing stimulation serves as a nonuniform gradual stretching of neuronal circuit delay loops and emerges as an essential mechanism in the formation of various types of neuronal timers. Synchronization emerges as a transient phenomenon without predefined precise matched synaptic delays. These findings are described in an experimental procedure where conditioned stimulations were enforced on a circuit of neurons embedded within a large-scale network of cortical cells in vitro, and are corroborated by neuronal simulations. They evidence a new cortical time scale based on tens of μs stretching of neuronal circuit delay loops per spike, and with realistic delays of a few milliseconds, synchronization emerges for a finite fraction of neuronal circuit delays.
AB - We show that the unavoidable increase in neuronal response latency to ongoing stimulation serves as a nonuniform gradual stretching of neuronal circuit delay loops and emerges as an essential mechanism in the formation of various types of neuronal timers. Synchronization emerges as a transient phenomenon without predefined precise matched synaptic delays. These findings are described in an experimental procedure where conditioned stimulations were enforced on a circuit of neurons embedded within a large-scale network of cortical cells in vitro, and are corroborated by neuronal simulations. They evidence a new cortical time scale based on tens of μs stretching of neuronal circuit delay loops per spike, and with realistic delays of a few milliseconds, synchronization emerges for a finite fraction of neuronal circuit delays.
UR - http://www.scopus.com/inward/record.url?scp=84870307849&partnerID=8YFLogxK
U2 - 10.1209/0295-5075/100/48003
DO - 10.1209/0295-5075/100/48003
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AN - SCOPUS:84870307849
SN - 0295-5075
VL - 100
JO - Lettere Al Nuovo Cimento
JF - Lettere Al Nuovo Cimento
IS - 4
M1 - 48003
ER -