Syncytial variant of nodular sclerosing Hodgkin's disease. A new clinicopathologic entity

Dina Ben‐Yehuda‐Salz*, Aaron Polliack, Arie Ben‐Yehuda, Noemi Ron, Elimelech Okon

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

30 Scopus citations

Abstract

The clinicopathologic and histopathologic features of an unusual morphologic variant of nodular sclerosing Hodgkin's Disease (HD) termed the syncytial variant has been reported recently.1 We report eight new cases with this unique morphology, identified by reviewing the histopathology of 58 patients with nodular sclerosing HD treated in our institute between 1982 and 1988. The clinicopathologic and histopathologic data of these cases are reported and we emphasize this new entity and the difficulties encountered in the morphologic diagnosis. All of the eight patients had a difficult initial clinical course, and were in a clinically advanced stage of the disease at the time of diagnosis. We cite a statistical comparison of the clinical features of the different forms of nodular sclerosing HD.

Original languageAmerican English
Pages (from-to)1167-1172
Number of pages6
JournalCancer
Volume65
Issue number5
DOIs
StatePublished - 1 Mar 1990
Externally publishedYes

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