Syntheses of β-dl-Aspartyl Peptides with Maleic Anhydride

Y. Liwschitz, A. Zilkha

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

β-df-Aspartyl peptides have been synthesized, starting with maleic anhydride. This was opened by the appropriate free amino acid esters to yield maleamic acids, to the double bond of which one mole of benzylamine was added. By hydrolysis of the resulting N-benzyl-β-dl-aspartyl dipeptide esters and subsequent hydrogenolysis, the free dipeptides were produced.

Original languageEnglish
Pages (from-to)1265-1266
Number of pages2
JournalJournal of the American Chemical Society
Volume77
Issue number5
DOIs
StatePublished - 1 Mar 1955

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