Syntheses of Hydroxyalkyl and Mercaptoalkyl Derivatives of Sulfur-containing Amino Acids

A. Zilkha; S. Rappoport

doi:10.1021/jo01039a060

Syntheses of Hydroxyalkyl and Mercaptoalkyl Derivatives of Sulfur-containing Amino Acids

A. Zilkha, S. Rappoport

Institute of Chemistry

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14 Scopus citations

Abstract

Some S-, N-, and S,N-hydroxyalkyl derivatives of cysteine, homocysteine, cystine, and methionine were prepared by the reaction of alkylene oxides or alkylene carbonates with the amino acids under basic conditions. S-Mercaptoalkyl derivatives of cysteine were obtained by a similar reaction with alkylene sulfides.

Original language	English
Pages (from-to)	1105-1107
Number of pages	3
Journal	Journal of Organic Chemistry
Volume	28
Issue number	4
DOIs	https://doi.org/10.1021/jo01039a060
State	Published - 1 Apr 1963

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title = "Syntheses of Hydroxyalkyl and Mercaptoalkyl Derivatives of Sulfur-containing Amino Acids",

abstract = "Some S-, N-, and S,N-hydroxyalkyl derivatives of cysteine, homocysteine, cystine, and methionine were prepared by the reaction of alkylene oxides or alkylene carbonates with the amino acids under basic conditions. S-Mercaptoalkyl derivatives of cysteine were obtained by a similar reaction with alkylene sulfides.",

author = "A. Zilkha and S. Rappoport",

year = "1963",

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doi = "10.1021/jo01039a060",

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N2 - Some S-, N-, and S,N-hydroxyalkyl derivatives of cysteine, homocysteine, cystine, and methionine were prepared by the reaction of alkylene oxides or alkylene carbonates with the amino acids under basic conditions. S-Mercaptoalkyl derivatives of cysteine were obtained by a similar reaction with alkylene sulfides.

AB - Some S-, N-, and S,N-hydroxyalkyl derivatives of cysteine, homocysteine, cystine, and methionine were prepared by the reaction of alkylene oxides or alkylene carbonates with the amino acids under basic conditions. S-Mercaptoalkyl derivatives of cysteine were obtained by a similar reaction with alkylene sulfides.

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Syntheses of Hydroxyalkyl and Mercaptoalkyl Derivatives of Sulfur-containing Amino Acids

Abstract

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