Synthesis and characterization of Au102(p -MBA)44 nanoparticles

Yael Levi-Kalisman; Pablo D. Jadzinsky; Nir Kalisman; Hironori Tsunoyama; Tatsuya Tsukuda; David A. Bushnell; Roger D. Kornberg

doi:10.1021/ja109131w

Synthesis and characterization of Au₁₀₂(p -MBA)₄₄ nanoparticles

Yael Levi-Kalisman, Pablo D. Jadzinsky, Nir Kalisman, Hironori Tsunoyama, Tatsuya Tsukuda, David A. Bushnell, Roger D. Kornberg

Research output: Contribution to journal › Article › peer-review

216 Scopus citations

Abstract

The synthesis of Au₁₀₂(p-MBA)₄₄ nanoparticles on a preparative scale in high yield is described. Various analytical methods are shown to give results consistent with the composition and known structure of the particles, showing the preparation is essentially homogeneous, and attesting to the validity of the methods as well. Derivatization of the particles with proteins and DNA is demonstrated, and conditions are described for imaging individual particles by cryo-EM at low electron dose, close to focus, conditions optimal for recording high-resolution details.

Original language	English
Pages (from-to)	2976-2982
Number of pages	7
Journal	Journal of the American Chemical Society
Volume	133
Issue number	9
DOIs	https://doi.org/10.1021/ja109131w
State	Published - 9 Mar 2011
Externally published	Yes

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10.1021/ja109131w

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title = "Synthesis and characterization of Au102(p -MBA)44 nanoparticles",

abstract = "The synthesis of Au102(p-MBA)44 nanoparticles on a preparative scale in high yield is described. Various analytical methods are shown to give results consistent with the composition and known structure of the particles, showing the preparation is essentially homogeneous, and attesting to the validity of the methods as well. Derivatization of the particles with proteins and DNA is demonstrated, and conditions are described for imaging individual particles by cryo-EM at low electron dose, close to focus, conditions optimal for recording high-resolution details.",

author = "Yael Levi-Kalisman and Jadzinsky, {Pablo D.} and Nir Kalisman and Hironori Tsunoyama and Tatsuya Tsukuda and Bushnell, {David A.} and Kornberg, {Roger D.}",

year = "2011",

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AU - Levi-Kalisman, Yael

AU - Jadzinsky, Pablo D.

AU - Kalisman, Nir

AU - Tsunoyama, Hironori

AU - Tsukuda, Tatsuya

AU - Bushnell, David A.

AU - Kornberg, Roger D.

PY - 2011/3/9

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AB - The synthesis of Au102(p-MBA)44 nanoparticles on a preparative scale in high yield is described. Various analytical methods are shown to give results consistent with the composition and known structure of the particles, showing the preparation is essentially homogeneous, and attesting to the validity of the methods as well. Derivatization of the particles with proteins and DNA is demonstrated, and conditions are described for imaging individual particles by cryo-EM at low electron dose, close to focus, conditions optimal for recording high-resolution details.

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JF - Journal of the American Chemical Society

IS - 9

ER -

Synthesis and characterization of Au₁₀₂(p -MBA)₄₄ nanoparticles

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