Synthesis and characterization of chiral enantiopure PC(sp3)P pincer ligands and their complexes

Yana Radchenko, Shrouq Mujahed, Sanaa Musa, Dmitri Gelman*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

This paper reports an efficient synthetic approach to preparing optically active PC(sp3)P pincer ligands and their complexes. The reported synthetic scheme relies on a simple and straightforward carbo-Diels–Alder reaction cycloaddition of a readily available phosphine precursor, 1,8-bis-(diphenylphosphino)anthracene (2) with enantiomerically pure bis-(methyl-(S)-lactyl) fumarate (3) leading to the formation of chromatographically resolvable diastereomers 4 and 4′ that can be converted into a pair of enantiomerically pure antipodes 1 and 1′. We demonstrated that no racemization occurs upon complexation and metalation of the bifunctional PC(sp3)P pincer ligands.

Original languageAmerican English
Article number120350
JournalInorganica Chimica Acta
Volume521
DOIs
StatePublished - 1 Jun 2021

Bibliographical note

Publisher Copyright:
© 2021 Elsevier B.V.

Keywords

  • Bifunctional catalysts
  • Chiral pincer complexes
  • Cooperative catalysis
  • PC(sp)P

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