TY - JOUR
T1 - Synthesis and characterization of chiral enantiopure PC(sp3)P pincer ligands and their complexes
AU - Radchenko, Yana
AU - Mujahed, Shrouq
AU - Musa, Sanaa
AU - Gelman, Dmitri
N1 - Publisher Copyright:
© 2021 Elsevier B.V.
PY - 2021/6/1
Y1 - 2021/6/1
N2 - This paper reports an efficient synthetic approach to preparing optically active PC(sp3)P pincer ligands and their complexes. The reported synthetic scheme relies on a simple and straightforward carbo-Diels–Alder reaction cycloaddition of a readily available phosphine precursor, 1,8-bis-(diphenylphosphino)anthracene (2) with enantiomerically pure bis-(methyl-(S)-lactyl) fumarate (3) leading to the formation of chromatographically resolvable diastereomers 4 and 4′ that can be converted into a pair of enantiomerically pure antipodes 1 and 1′. We demonstrated that no racemization occurs upon complexation and metalation of the bifunctional PC(sp3)P pincer ligands.
AB - This paper reports an efficient synthetic approach to preparing optically active PC(sp3)P pincer ligands and their complexes. The reported synthetic scheme relies on a simple and straightforward carbo-Diels–Alder reaction cycloaddition of a readily available phosphine precursor, 1,8-bis-(diphenylphosphino)anthracene (2) with enantiomerically pure bis-(methyl-(S)-lactyl) fumarate (3) leading to the formation of chromatographically resolvable diastereomers 4 and 4′ that can be converted into a pair of enantiomerically pure antipodes 1 and 1′. We demonstrated that no racemization occurs upon complexation and metalation of the bifunctional PC(sp3)P pincer ligands.
KW - Bifunctional catalysts
KW - Chiral pincer complexes
KW - Cooperative catalysis
KW - PC(sp)P
UR - http://www.scopus.com/inward/record.url?scp=85103049331&partnerID=8YFLogxK
U2 - 10.1016/j.ica.2021.120350
DO - 10.1016/j.ica.2021.120350
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AN - SCOPUS:85103049331
SN - 0020-1693
VL - 521
JO - Inorganica Chimica Acta
JF - Inorganica Chimica Acta
M1 - 120350
ER -