Synthesis, Characterizaiton, and Biological Activity of Some Thiazole Hydrazines: Activities of Some Newer Schiff Bases derived from pyrimidine-5-Carbonitrile.

Vishnu A. Gore; Akshay Tangade; Dhanaji P. Rajani; Avi Jacob Domb

Synthesis, Characterizaiton, and Biological Activity of Some Thiazole Hydrazines: Activities of Some Newer Schiff Bases derived from pyrimidine-5-Carbonitrile.

Vishnu A. Gore
, Akshay Tangade
, Dhanaji P. Rajani
, Avi Jacob Domb

School of Pharmacy

Research output: Contribution to journal › Article › peer-review

Abstract

A new series of Schiff base derived from pyrimidine were synthesised. Schiff bases were obtained by the condensation of 1-ethyl-4-(4-fluorophenyl)-2-hydrazinyl-1,6-dihydro-6-oxopyrimidine-5- carbonitrile with aromatic aldehyde. The chemical structure of newly synthesized compound was confirmed by ¹H NMR, FTIR and Mass spectroscopy.

Original language	English
Pages (from-to)	55-62
Number of pages	7
Journal	Chemistry & Biology Interface
Volume	13
Issue number	2
State	Published - 1 Mar 2023

Keywords

Schiff bases
Mass spectrometry
Antibacterial agents
Aromatic aldehydes
Chemical synthesis
Carbonitriles
Pharmaceutical and medicine manufacturing

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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title = "Synthesis, Characterizaiton, and Biological Activity of Some Thiazole Hydrazines: Activities of Some Newer Schiff Bases derived from pyrimidine-5-Carbonitrile.",

abstract = "A new series of Schiff base derived from pyrimidine were synthesised. Schiff bases were obtained by the condensation of 1-ethyl-4-(4-fluorophenyl)-2-hydrazinyl-1,6-dihydro-6-oxopyrimidine-5- carbonitrile with aromatic aldehyde. The chemical structure of newly synthesized compound was confirmed by ¹H NMR, FTIR and Mass spectroscopy. ",

keywords = "Schiff bases, Mass spectrometry, Antibacterial agents, Aromatic aldehydes, Chemical synthesis, Carbonitriles, Pharmaceutical and medicine manufacturing",

author = "Gore, \{Vishnu A.\} and Akshay Tangade and Rajani, \{Dhanaji P.\} and Domb, \{Avi Jacob\}",

year = "2023",

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journal = "Chemistry \& Biology Interface",

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publisher = "Indian Society of Chemists \& Biologists",

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T2 - Activities of Some Newer Schiff Bases derived from pyrimidine-5-Carbonitrile.

AU - Gore, Vishnu A.

AU - Tangade, Akshay

AU - Rajani, Dhanaji P.

AU - Domb, Avi Jacob

PY - 2023/3/1

Y1 - 2023/3/1

N2 - A new series of Schiff base derived from pyrimidine were synthesised. Schiff bases were obtained by the condensation of 1-ethyl-4-(4-fluorophenyl)-2-hydrazinyl-1,6-dihydro-6-oxopyrimidine-5- carbonitrile with aromatic aldehyde. The chemical structure of newly synthesized compound was confirmed by ¹H NMR, FTIR and Mass spectroscopy.

AB - A new series of Schiff base derived from pyrimidine were synthesised. Schiff bases were obtained by the condensation of 1-ethyl-4-(4-fluorophenyl)-2-hydrazinyl-1,6-dihydro-6-oxopyrimidine-5- carbonitrile with aromatic aldehyde. The chemical structure of newly synthesized compound was confirmed by ¹H NMR, FTIR and Mass spectroscopy.

KW - Schiff bases

KW - Mass spectrometry

KW - Antibacterial agents

KW - Aromatic aldehydes

KW - Chemical synthesis

KW - Carbonitriles

KW - Pharmaceutical and medicine manufacturing

M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???

SN - 2249-4820

VL - 13

SP - 55

EP - 62

JO - Chemistry & Biology Interface

JF - Chemistry & Biology Interface

IS - 2

ER -

Synthesis, Characterizaiton, and Biological Activity of Some Thiazole Hydrazines: Activities of Some Newer Schiff Bases derived from pyrimidine-5-Carbonitrile.

Abstract

Keywords

UN SDGs

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