Synthesis, Characterizaiton, and Biological Activity of Some Thiazole Hydrazines: Activities of Some Newer Schiff Bases derived from pyrimidine-5-Carbonitrile.

Vishnu A. Gore; Akshay Tangade; Dhanaji P. Rajani; Avi Jacob Domb

Synthesis, Characterizaiton, and Biological Activity of Some Thiazole Hydrazines: Activities of Some Newer Schiff Bases derived from pyrimidine-5-Carbonitrile.

Vishnu A. Gore
, Akshay Tangade
, Dhanaji P. Rajani
, Avi Jacob Domb

School of Pharmacy

Research output: Contribution to journal › Article › peer-review

Abstract

A new series of Schiff base derived from pyrimidine were synthesised. Schiff bases were obtained by the condensation of 1-ethyl-4-(4-fluorophenyl)-2-hydrazinyl-1,6-dihydro-6-oxopyrimidine-5- carbonitrile with aromatic aldehyde. The chemical structure of newly synthesized compound was confirmed by ¹H NMR, FTIR and Mass spectroscopy.

Original language	English
Pages (from-to)	55-62
Number of pages	7
Journal	Chemistry & Biology Interface
Volume	13
Issue number	2
State	Published - 1 Mar 2023

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Keywords

Schiff bases
Mass spectrometry
Antibacterial agents
Aromatic aldehydes
Chemical synthesis
Carbonitriles
Pharmaceutical and medicine manufacturing

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title = "Synthesis, Characterizaiton, and Biological Activity of Some Thiazole Hydrazines: Activities of Some Newer Schiff Bases derived from pyrimidine-5-Carbonitrile.",

abstract = "A new series of Schiff base derived from pyrimidine were synthesised. Schiff bases were obtained by the condensation of 1-ethyl-4-(4-fluorophenyl)-2-hydrazinyl-1,6-dihydro-6-oxopyrimidine-5- carbonitrile with aromatic aldehyde. The chemical structure of newly synthesized compound was confirmed by ¹H NMR, FTIR and Mass spectroscopy. ",

keywords = "Schiff bases, Mass spectrometry, Antibacterial agents, Aromatic aldehydes, Chemical synthesis, Carbonitriles, Pharmaceutical and medicine manufacturing",

author = "Gore, \{Vishnu A.\} and Akshay Tangade and Rajani, \{Dhanaji P.\} and Domb, \{Avi Jacob\}",

year = "2023",

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T2 - Activities of Some Newer Schiff Bases derived from pyrimidine-5-Carbonitrile.

AU - Gore, Vishnu A.

AU - Tangade, Akshay

AU - Rajani, Dhanaji P.

AU - Domb, Avi Jacob

PY - 2023/3/1

Y1 - 2023/3/1

N2 - A new series of Schiff base derived from pyrimidine were synthesised. Schiff bases were obtained by the condensation of 1-ethyl-4-(4-fluorophenyl)-2-hydrazinyl-1,6-dihydro-6-oxopyrimidine-5- carbonitrile with aromatic aldehyde. The chemical structure of newly synthesized compound was confirmed by ¹H NMR, FTIR and Mass spectroscopy.

AB - A new series of Schiff base derived from pyrimidine were synthesised. Schiff bases were obtained by the condensation of 1-ethyl-4-(4-fluorophenyl)-2-hydrazinyl-1,6-dihydro-6-oxopyrimidine-5- carbonitrile with aromatic aldehyde. The chemical structure of newly synthesized compound was confirmed by ¹H NMR, FTIR and Mass spectroscopy.

KW - Schiff bases

KW - Mass spectrometry

KW - Antibacterial agents

KW - Aromatic aldehydes

KW - Chemical synthesis

KW - Carbonitriles

KW - Pharmaceutical and medicine manufacturing

M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???

SN - 2249-4820

VL - 13

SP - 55

EP - 62

JO - Chemistry & Biology Interface

JF - Chemistry & Biology Interface

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ER -

Synthesis, Characterizaiton, and Biological Activity of Some Thiazole Hydrazines: Activities of Some Newer Schiff Bases derived from pyrimidine-5-Carbonitrile.

Abstract

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Keywords

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