Abstract
Asymmetrical 2,2′-((ethane-1,2-diylbis((2-hydroxyethyl)azanediyl))bis(methylene))diphenol substituted compounds and their C1-symmetrical diaminobis(phenolato)-bis(alkoxo) titanium(iv) complexes were synthesized, with one symmetrical analogue. X-ray crystallography corroborated tight ligand binding. Different substitutions on the two aromatic rings enabled fine-tuning of the complex properties, giving enhanced solubility, high anticancer activity (IC50 < 4 μM), and significant hydrolytic stability.
| Original language | English |
|---|---|
| Pages (from-to) | 6423-6426 |
| Number of pages | 4 |
| Journal | Dalton Transactions |
| Volume | 50 |
| Issue number | 19 |
| DOIs | |
| State | Published - 21 May 2021 |
Bibliographical note
Publisher Copyright:© 2021 The Royal Society of Chemistry.
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