Synthesis of DL-p-trimethylsitylphenylalanine

M. A.X. Frankel; David Gertner; Avinoam Shenhar; Albert Zilkha

Synthesis of DL-p-trimethylsitylphenylalanine

M. A.X. Frankel^*, David Gertner, Avinoam Shenhar, Albert Zilkha

^*Corresponding author for this work

Institute of Chemistry

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

DL-p-Trimethylsilylphenylalanine has been prepared in good yield by condensation of 4-trimethylsilylbenzyl bromide with diethyl formamidomalonate, followed by mild hydrolysis and decarboxylation of the resulting disodium α-(4-trimethylsilylbenzyl)formamidomalonate. Its N-carboxyanhydride was obtained on reaction of the amino-acid with carbonyl chloride, and it has been polymerised in pyridine.

Original language	English
Pages (from-to)	5137-5140
Number of pages	4
Journal	Journal of the Chemical Society
State	Published - 1963

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title = "Synthesis of DL-p-trimethylsitylphenylalanine",

abstract = "DL-p-Trimethylsilylphenylalanine has been prepared in good yield by condensation of 4-trimethylsilylbenzyl bromide with diethyl formamidomalonate, followed by mild hydrolysis and decarboxylation of the resulting disodium α-(4-trimethylsilylbenzyl)formamidomalonate. Its N-carboxyanhydride was obtained on reaction of the amino-acid with carbonyl chloride, and it has been polymerised in pyridine.",

author = "Frankel, \{M. A.X.\} and David Gertner and Avinoam Shenhar and Albert Zilkha",

year = "1963",

language = "אנגלית",

pages = "5137--5140",

journal = "Journal of the Chemical Society",

issn = "0368-1769",

publisher = "Chemical Society",

}

TY - JOUR

T1 - Synthesis of DL-p-trimethylsitylphenylalanine

AU - Frankel, M. A.X.

AU - Gertner, David

AU - Shenhar, Avinoam

AU - Zilkha, Albert

PY - 1963

Y1 - 1963

N2 - DL-p-Trimethylsilylphenylalanine has been prepared in good yield by condensation of 4-trimethylsilylbenzyl bromide with diethyl formamidomalonate, followed by mild hydrolysis and decarboxylation of the resulting disodium α-(4-trimethylsilylbenzyl)formamidomalonate. Its N-carboxyanhydride was obtained on reaction of the amino-acid with carbonyl chloride, and it has been polymerised in pyridine.

AB - DL-p-Trimethylsilylphenylalanine has been prepared in good yield by condensation of 4-trimethylsilylbenzyl bromide with diethyl formamidomalonate, followed by mild hydrolysis and decarboxylation of the resulting disodium α-(4-trimethylsilylbenzyl)formamidomalonate. Its N-carboxyanhydride was obtained on reaction of the amino-acid with carbonyl chloride, and it has been polymerised in pyridine.

UR - https://www.scopus.com/pages/publications/55549117872

M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???

AN - SCOPUS:55549117872

SN - 0368-1769

SP - 5137

EP - 5140

JO - Journal of the Chemical Society

JF - Journal of the Chemical Society

ER -

Synthesis of DL-p-trimethylsitylphenylalanine

Abstract

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