Abstract
Indazoles is an important class of heterocyclic compounds having a wide range of biological and pharmaceutical applications. There is enormous potential in the synthesis of novel heterocyclic systems to be used as building blocks for the next generation of pharmaceuticals as anti-bacterial, anti-depressant and anti-inflammatory. Fused aromatic 1H and 2H-indazoles are well recognized for anti-hypertensive and anti-cancer properties. The present review focuses on novel routes of their synthesis and various biological activities.
Original language | English |
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Pages (from-to) | 707-731 |
Number of pages | 25 |
Journal | European Journal of Medicinal Chemistry |
Volume | 90 |
DOIs | |
State | Published - 27 Jan 2015 |
Bibliographical note
Publisher Copyright:© 2014 Elsevier Masson SAS.
Keywords
- Antipsychotic
- Antiretroviral
- Antitumor
- Axitinib
- Chronic pain
- Narcotic