Abstract
The design and synthesis of C3- symmetric or pseudo-C3-symmetric ligands present a particular challenge because the molecular frames available for fitting C3 symmetry are rare. Herein, we report on the synthesis and characterization of new C3-symmetric tripodal TripTOX ligands, based on the rigid triptycene backbone, and on their successful application in the asymmetric copper-catalyzed aziridination reaction. The ligand showed good to excellent performance in the copper-catalyzed asymmetric aziridination of chalcones. The catalyst derived from the new ligand appears to be the catalyst of choice when substrates have a coordinating nature.
Original language | English |
---|---|
Article number | 121804 |
Journal | Journal of Organometallic Chemistry |
Volume | 941 |
DOIs | |
State | Published - 7 Jun 2021 |
Bibliographical note
Publisher Copyright:© 2021 Elsevier B.V.
Keywords
- C3-symmetric
- aziridination
- copper-catalyzed
- enantioselective
- oxazoline
- triptycene