TY - JOUR
T1 - Synthetic ultrashort cationic lipopeptides induce systemic plant defense responses against bacterial and fungal pathogens
AU - Brotman, Yariv
AU - Makovitzki, Arik
AU - Shai, Yechiel
AU - Chet, Ilan
AU - Viterbo, Ada
PY - 2009/8
Y1 - 2009/8
N2 - A new family of synthetic, membrane-active, ultrashort lipopeptides composed of only four amino acids linked to fatty acids was tested for the ability to induce systemic resistance and defense responses in plants. We found that two peptides wherein the third residue is a D-enantiomer (italic), C 16-KKKK and C16-KLLK, can induce medium alkalinization of tobacco suspension-cultured cells and expression of defense-related genes in cucumber and Arabidopsis seedlings. Moreover, these compounds can prime systemic induction of antimicrobial compounds in cucumber leaves similarly to the plant-beneficial fungus Trichoderma asperellum T203 and provide systemic protection against the phytopathogens Botrytis cinerea B05, Pseudomonas syringae pv. lachrimans, and P. syringae pv. tomato DC3000. Thus, short cationic lipopeptides are a new category of compounds with potentially high utility in the induction of systemic resistance in plants.
AB - A new family of synthetic, membrane-active, ultrashort lipopeptides composed of only four amino acids linked to fatty acids was tested for the ability to induce systemic resistance and defense responses in plants. We found that two peptides wherein the third residue is a D-enantiomer (italic), C 16-KKKK and C16-KLLK, can induce medium alkalinization of tobacco suspension-cultured cells and expression of defense-related genes in cucumber and Arabidopsis seedlings. Moreover, these compounds can prime systemic induction of antimicrobial compounds in cucumber leaves similarly to the plant-beneficial fungus Trichoderma asperellum T203 and provide systemic protection against the phytopathogens Botrytis cinerea B05, Pseudomonas syringae pv. lachrimans, and P. syringae pv. tomato DC3000. Thus, short cationic lipopeptides are a new category of compounds with potentially high utility in the induction of systemic resistance in plants.
UR - http://www.scopus.com/inward/record.url?scp=68549098046&partnerID=8YFLogxK
U2 - 10.1128/AEM.00724-09
DO - 10.1128/AEM.00724-09
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C2 - 19542326
AN - SCOPUS:68549098046
SN - 0099-2240
VL - 75
SP - 5373
EP - 5379
JO - Applied and Environmental Microbiology
JF - Applied and Environmental Microbiology
IS - 16
ER -