Here we review T-cell vaccination (TCV), a cell-based, generic approach to immune regulation. We describe TCV clinical trials in multiple sclerosis and other autoimmune diseases; we analyze the immune regulatory mechanisms activated by TCV; we examine the potential of public T cells as TCV mediators, and we discuss the physiology of immune regulation in the light of TCV.
|Original language||American English|
|Title of host publication||Translational Neuroimmunology in Multiple Sclerosis|
|Subtitle of host publication||From Disease Mechanisms to Clinical Applications|
|Number of pages||17|
|State||Published - 3 Aug 2016|
Bibliographical notePublisher Copyright:
© 2016 Elsevier Inc. All rights reserved.
- Cell therapy
- T cells
- T-cell vaccination