T-Cell Vaccination: An Insight Into T-Cell Regulation

I. R. Cohen*, N. Friedman, F. J. Quintana

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review


Here we review T-cell vaccination (TCV), a cell-based, generic approach to immune regulation. We describe TCV clinical trials in multiple sclerosis and other autoimmune diseases; we analyze the immune regulatory mechanisms activated by TCV; we examine the potential of public T cells as TCV mediators, and we discuss the physiology of immune regulation in the light of TCV.

Original languageAmerican English
Title of host publicationTranslational Neuroimmunology in Multiple Sclerosis
Subtitle of host publicationFrom Disease Mechanisms to Clinical Applications
PublisherElsevier Inc.
Number of pages17
ISBN (Electronic)9780128020074
ISBN (Print)9780128019146
StatePublished - 3 Aug 2016
Externally publishedYes

Bibliographical note

Publisher Copyright:
© 2016 Elsevier Inc. All rights reserved.


  • Antibodies
  • Antiergotype
  • Antiidiotype
  • Autoimmunity
  • Cell therapy
  • T cells
  • T-cell vaccination


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