Abstract
Novel silica gel-catalysed reactions of dihydroartemisinin 1b to deoxyartemisinin 11 and 11 β-hydroxy-11-epidihydroartemisinin 8 to compound 9 under mild conditions are described. The structures of the products were determined by mass spectrometry and 1D- and 2D-NMR spectroscopy. A mechanism for their formation is proposed.
Original language | English |
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Pages (from-to) | 843-846 |
Number of pages | 4 |
Journal | Journal of the Chemical Society, Perkin Transactions 1 |
Issue number | 7 |
DOIs | |
State | Published - 1994 |