Targeting signal transduction for disease therapy

Alexander Levitzki

doi:10.1007/BF02990952

Targeting signal transduction for disease therapy

Alexander Levitzki^*

^*Corresponding author for this work

Alexander Silberman Institute of Life Sciences

Research output: Contribution to journal › Article › peer-review

21 Scopus citations

Abstract

With the advance in the molecular understanding of cancers and proliferative disorders new approaches to managing these diseases may become feasible. It has been recognized that a key feature of these diseases is the pathological alteration in the molecular machineries of signalling pathways. This recognition which began to emerge in the early 1980s induced us to explore the possibility of targetting the aberrant signalling pathways for disease therapy. I now present evidence for the validity of the approach.

Original language	English
Pages (from-to)	83-89
Number of pages	7
Journal	Medical Oncology
Volume	14
Issue number	2
DOIs	https://doi.org/10.1007/BF02990952
State	Published - Jun 1997

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Disease therapy
Epidermal growth factor
Platelet derived growth factor
Targetting signal transduction

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10.1007/BF02990952

Cite this

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abstract = "With the advance in the molecular understanding of cancers and proliferative disorders new approaches to managing these diseases may become feasible. It has been recognized that a key feature of these diseases is the pathological alteration in the molecular machineries of signalling pathways. This recognition which began to emerge in the early 1980s induced us to explore the possibility of targetting the aberrant signalling pathways for disease therapy. I now present evidence for the validity of the approach.",

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Targeting signal transduction for disease therapy

Abstract

UN SDGs

Keywords

Access to Document

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