Temporal and spatial frequencies interact in the contrast transfer function of the pattern electroretinogram

G. Ben-Shlomo, M. Bach*, R. Ofri

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

The contrast transfer function (CTF) of the pattern electroretinogram (PERG) depends on temporal frequency. For transient stimulation it is fully linear; at faster stimulation rates it becomes strongly non-linear with an accelerated shape. In this study we investigated a range of stimulus parameters with the aim of studying the influence of temporal and spatial frequencies, as well as contrast levels, on the CTF; effects were quantified via an "index of linearity" IL. Both reversal rate and check size influenced linearity (p < .001), examples: At a constant check size of 0.8°, 7.7 rps: IL = 1.0; 0.8°/24 rps: IL = 0.5; at a constant reversal rate of 19 rps, IL was 0.5 for 0.8°, but rose to 0.8 both for 0.2° and 18°. The reason for this complex response surface remains a puzzle, it cannot be explained by varying parvo/magnocellular contributions, and its possible influences on recordings in patients merit further studies.

Original languageAmerican English
Pages (from-to)1992-1999
Number of pages8
JournalVision Research
Volume47
Issue number15
DOIs
StatePublished - Jul 2007

Bibliographical note

Funding Information:
This study was made possible by a travel grant from the German Academic Exchange Service (DAAD), and support from the Joseph Alexander Foundation and the Alberto Moscona Foundation.

Keywords

  • Check size
  • Contrast
  • Contrast transfer characteristic
  • Linearity
  • PERG
  • Pattern ERG
  • Temporal frequency

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