Testing and characterizing the simple pore

W. R. Lieb*, W. D. Stein

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

37 Scopus citations

Abstract

1. 1. We define a simple (or singly-occupied) pore and show that any pore which is fully occupied by a single substrate particle behaves as a simple pore at the level of steady-state analysis. 2. 2. The analysis is independent of assumptions as to (a) symmetry, (b) equilibrium, (c) the distribution of electrical potential in the membrane, and (d) the presence or absence of unstirred layers. 3. 3. We suggest simple experimental procedures involving only one substrate, the results of which can be used to test for and characterize the simple pore. For ions, only electrical measurements are needed.

Original languageEnglish
Pages (from-to)165-177
Number of pages13
JournalBiochimica et Biophysica Acta - Biomembranes
Volume373
Issue number2
DOIs
StatePublished - 10 Dec 1974

Fingerprint

Dive into the research topics of 'Testing and characterizing the simple pore'. Together they form a unique fingerprint.

Cite this