Abstract
Immune response genes determine the magnitude of many immune responses. A low response is often ascribed to a genetic defect. Here Irun Cohen argues that a poor response instead reflects a heightened sensitivity to the conditions in which antigen is encountered. When these are optimal the response is normal. Poor responders thus have the advantage of a greater fexibility of response over individuals who respond strongly regardless of prevailing circumstances.
Original language | English |
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Pages (from-to) | 147-148 |
Number of pages | 2 |
Journal | Immunology Today |
Volume | 6 |
Issue number | 5 |
DOIs | |
State | Published - May 1985 |
Externally published | Yes |