The bacterial second messenger c-di-GMP: Mechanisms of signalling

Erez Mills; Ingrid S. Pultz; Hemantha D. Kulasekara; Samuel I. Miller

doi:10.1111/j.1462-5822.2011.01619.x

The bacterial second messenger c-di-GMP: Mechanisms of signalling

Erez Mills
, Ingrid S. Pultz
, Hemantha D. Kulasekara
, Samuel I. Miller^*

^*Corresponding author for this work

Research output: Contribution to journal › Short survey › peer-review

110 Scopus citations

Abstract

Cyclic-di-GMP (c-di-GMP) regulates many important bacterial processes. Freely diffusible intracellular c-di-GMP is determined by the action of metabolizing enzymes that allow integration of numerous input signals. c-di-GMP specifically regulates multiple cellular processes by binding to diverse target molecules. This review highlights important questions in research into the mechanisms of c-di-GMP signalling and its role in bacterial physiology.

Original language	English
Pages (from-to)	1122-1129
Number of pages	8
Journal	Cellular Microbiology
Volume	13
Issue number	8
DOIs	https://doi.org/10.1111/j.1462-5822.2011.01619.x
State	Published - Aug 2011
Externally published	Yes

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10.1111/j.1462-5822.2011.01619.x

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title = "The bacterial second messenger c-di-GMP: Mechanisms of signalling",

abstract = "Cyclic-di-GMP (c-di-GMP) regulates many important bacterial processes. Freely diffusible intracellular c-di-GMP is determined by the action of metabolizing enzymes that allow integration of numerous input signals. c-di-GMP specifically regulates multiple cellular processes by binding to diverse target molecules. This review highlights important questions in research into the mechanisms of c-di-GMP signalling and its role in bacterial physiology.",

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AB - Cyclic-di-GMP (c-di-GMP) regulates many important bacterial processes. Freely diffusible intracellular c-di-GMP is determined by the action of metabolizing enzymes that allow integration of numerous input signals. c-di-GMP specifically regulates multiple cellular processes by binding to diverse target molecules. This review highlights important questions in research into the mechanisms of c-di-GMP signalling and its role in bacterial physiology.

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The bacterial second messenger c-di-GMP: Mechanisms of signalling

Abstract

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