The "Brainy Side" of Human Embryonic Stem Cells

Eran Hornstein, Nissim Benvenisty*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

14 Scopus citations

Abstract

The recent isolation of human embryonic stem (ES) cells is evoking great hopes for their future utilization in cell-replacement therapies and human development research. The hallmarks of ES cells, pluripotency and self-renewal capacity, suggest an infinite source for tissues of virtually all desired types. Specifically, human ES cells may potentially be the basis for effective treatments of a wide range of human neurodegenerative disorders. To enable the translation of this novel biomedical field into the clinic, mechanisms that control the differentiation of human embryonic stem cells into fully functional neuronal cells should be analyzed and controlled.

Original languageEnglish
Pages (from-to)169-173
Number of pages5
JournalJournal of Neuroscience Research
Volume76
Issue number2
DOIs
StatePublished - 15 Apr 2004

Keywords

  • Central nervous system
  • Differentiation
  • Human embryonic stem cells
  • Neuron

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